1p LSD microdose Canada

Microdosing is a popular practice among tech industry “biohackers,” seasoned “psychonauts,” and anyone seeking a mild psychedelic shift in perspective. Microdosing is ingesting a small amount of a psychoactive substance, such as LSD or psilocybin, to reap the advantages of that substance without suffering the full effects of taking a full dose.


The structure of 1-propionyl lysergic acid diethylamide, or 1P-LSD, is comparable to but not identical to that of the original molecule. Although its precise mechanisms of action remain unknown, 1P-LSD may be a "prodrug" of LSD, meaning it could convert to LSD in the body. While studies on mice reveal that 1P-LSD is 38% as potent as LSD, the same may not be true for humans. The two compounds are said to have similar effects by many people.

Since 1P-LSD differs somewhat from ordinary LSD at the chemical level, it can skirt prohibition in countries like Canada. Even though thousands of users use 1P-LSD every year, the drug is only sold online and advertised as a research tool, not for human consumption. Users of 1P-LSD who adhere to the protocol proposed by psychologist and microdosing specialist James Fadiman — to microdose once every four days — report an improved sense of well-being and togetherness, as well as heightened attention and a mild boost in energy.